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Redefining Thalamic Vascularization Vicariously Through Gerald Percheron: A Historical Vignette.
MedLine Citation:
PMID:  23314026     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Gerard Percheron, M.D., a practicing neurologist and prolific researcher at the Institute Nationale de la Sante et de la Recherche Medicale, made significant and valuable contributions to medicine, in particular, to the vascular anatomy of the basal ganglia. His particular interest in the thalamus eventually led to the identification of an anatomical variation in its vascular supply. This newly identified artery was subsequently named the artery of Percheron (AOP). Given the estimated prevalence of the AOP in up to one-third the population and its significant proportion of all thalamic infarcts, it is necessary for physicians to be aware of this anatomical vascular variant and its clinical consequences. While occlusion of the AOP may present similar to other arterial thalamic occlusions, it can be identified through susceptibility-weighted imaging and ruled out with conventional or magnetic resonance angiography. Occlusion of the artery of Percheron typically causes a simultaneous and symmetric infarction. Treatment efficacy is time-dependent and necessitates thrombolytics and anticoagulative medications. Here, we trace a course from the artery's initial description in 1973 to its current implications in cerebro-vascular stroke, and offer a synopsis of the proposed treatment.
Authors:
Nitin Agarwal; Amit Chaudhari; David R Hansberry; Charles J Prestigiacomo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  World neurosurgery     Volume:  -     ISSN:  1878-8750     ISO Abbreviation:  World Neurosurg     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101528275     Medline TA:  World Neurosurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Affiliation:
Department of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
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