Document Detail

Red palm oil: nutritional, physiological and therapeutic roles in improving human wellbeing and quality of life.
MedLine Citation:
PMID:  20095133     Owner:  NLM     Status:  MEDLINE    
The link between dietary fats and cardiovascular disease has created a growing interest in dietary red palm oil research. Also, the link between nutrition and health, oxidative stress and the severity or progression of disease has stimulated further interest in the potential role of red palm oil (a natural antioxidant product) to improve oxidative status by reducing oxidative stress in patients with cardiovascular disease, cancer and other chronic diseases. In spite of its level of saturated fatty acid content (50%), red palm oil has not been found to promote atherosclerosis and/or arterial thrombosis. This is probably due to the ratio of its saturated fatty acid to unsaturated fatty acid content and its high concentration of antioxidants such as beta-carotene, tocotrienols, tocopherols and vitamin E. It has also been reported that the consumption of red palm oil reduces the level of endogenous cholesterol, and this seems to be due to the presence of the tocotrienols and the peculiar isomeric position of its fatty acids. The benefits of red palm oil to health include a reduction in the risk of arterial thrombosis and/or atherosclerosis, inhibition of endogenous cholesterol biosynthesis, platelet aggregation, a reduction in oxidative stress and a reduction in blood pressure. It has also been shown that dietary red palm oil, taken in moderation in animals and humans, promotes the efficient utilisation of nutrients, activates hepatic drug metabolising enzymes, facilitates the haemoglobinisation of red blood cells and improves immune function. This review provides a comprehensive overview of the nutritional, physiological and biochemical roles of red palm oil in improving wellbeing and quality of life.
O O Oguntibeju; A J Esterhuyse; E J Truter
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British journal of biomedical science     Volume:  66     ISSN:  0967-4845     ISO Abbreviation:  Br. J. Biomed. Sci.     Publication Date:  2009  
Date Detail:
Created Date:  2010-01-25     Completed Date:  2010-06-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9309208     Medline TA:  Br J Biomed Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  216-22     Citation Subset:  IM    
Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa.
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MeSH Terms
Antioxidants / pharmacology
Breast Neoplasms / drug therapy
Cardiovascular Diseases / prevention & control*
Carotenoids / analysis
Child, Preschool
Dietary Fats, Unsaturated / administration & dosage
Disease Models, Animal
Hypercholesterolemia / prevention & control
Nutritive Value
Pancreatitis, Chronic / drug therapy
Plant Oils / chemistry*,  pharmacology,  therapeutic use*
Quality of Life*
Tocotrienols / analysis,  pharmacology
Vitamin A / analysis
Vitamin A Deficiency / blood,  prevention & control*
Young Adult
Reg. No./Substance:
0/Antioxidants; 0/Dietary Fats, Unsaturated; 0/Plant Oils; 0/Tocotrienols; 11103-57-4/Vitamin A; 36-88-4/Carotenoids; 8002-75-3/palm oil

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