Document Detail


Red-man syndrome after vancomycin: potential cross-reactivity with teicoplanin.
MedLine Citation:
PMID:  10396588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a patient with infective endocarditis who developed a severe form of Red-man syndrome after vancomycin. On substituting the antibiotic to teicoplanin, the patient went on to develop a dramatic pyrexia which settled only after the teicoplanin was discontinued. This suggested that there may be an element of cross-reactivity between teicoplanin and vancomycin in such patients and that teicoplanin may not be the most appropriate substitute in all cases of vancomycin-induced Red-man syndrome.
Authors:
C Khurana; M A de Belder
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  75     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-07-22     Completed Date:  1999-07-22     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  41-3     Citation Subset:  IM    
Affiliation:
Cardiothoracic Division, South Cleveland Hospital, Middlesbrough, UK.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Bacterial Agents / adverse effects*
Cross Reactions
Dermatitis, Exfoliative / chemically induced
Endocarditis, Bacterial / drug therapy
Fever / chemically induced
Humans
Male
Purpura, Schoenlein-Henoch / chemically induced
Teicoplanin / adverse effects*
Vancomycin / adverse effects*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 1404-90-6/Vancomycin; 61036-62-2/Teicoplanin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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