Document Detail


Red cell membrane phospholipid abnormalities in the hemolytic uremic syndrome.
MedLine Citation:
PMID:  7214747     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight patients with the hemolytic uremic syndrome had depression of percentage of red cell phosphatidyl ethanolamine content. Five patients also had subnormal plasma tocopherol levels. In addition all patients had significant increases in total plasma lipids which could contribute to peroxidative damage. The association of depressed red cell phosphatidyl ethanolamine and plasma tocopherol levels is suggestive of peroxidative damage, and may contribute to the hemolysis in this syndrome.
Authors:
S O'Regan; R W Chesney; B S Kaplan; K N Drummond
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical nephrology     Volume:  15     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  14-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Erythrocyte Membrane / metabolism*
Erythrocytes / metabolism*
Female
Hemolytic-Uremic Syndrome / blood*
Humans
Infant
Lipids / blood
Male
Phosphatidylcholines / blood
Phosphatidylethanolamines / blood
Phospholipids / blood*
Sphingomyelins / blood
Vitamin E / blood
Grant Support
ID/Acronym/Agency:
AM 19489/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
0/Lipids; 0/Phosphatidylcholines; 0/Phosphatidylethanolamines; 0/Phospholipids; 0/Sphingomyelins; 1406-18-4/Vitamin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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