Document Detail


Red cell glucose-6-phosphate dehydrogenase phenotypes in Iraq.
MedLine Citation:
PMID:  15330559     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We attempted to characterize biochemically glucose-6-phosphate dehydrogenase (G6PD) variants in Iraqi individuals. Thus 758 healthy Iraqi males aged 18-60 years were randomly selected and 46 (6.1%) were G6PD deficient. Although the predominant non-deficient G6PD phenotype was G6PD B (92.6%), G6PD A+ was found in polymorphic frequency (1.3%). In the deficient group, 31 cases were fully characterized, including 17 cases with features consistent with G6PD Mediterranean variant, while 12 had other biochemical features and were labelled as non-Mediterranean variant. The remaining two deficient cases were characterized as G6PD A- variant. The presence of a significant number of non-Mediterranean variant was unexpected and may be related to the more heterogeneous background of the Iraqi people.
Authors:
F A Hilmi; N A Al-Allawi; M Rassam; G Al-Shamma; A Al-Hashimi
Related Documents :
20013269 - Microscopic polyangiitis in an adolescent presenting as severe anemia and syncope.
16937479 - Alpha-1-antitrypsin deficiency resulting in a hitherto unseen presentation of hepatocel...
1509529 - Beta-ketothiolase deficiency. a case report.
11071669 - Hereditary hemochromatosis in a patient with congenital dyserythropoietic anemia.
11763399 - Rosacea fulminans triggered by high-dose vitamins b6 and b12.
3964529 - Abnormal vitamin k metabolism in the presence of normal clotting factor activity in fac...
19709769 - The heart and cardiovascular system in the qur'an and hadeeth.
9643599 - Desmoplastic variant of ameloblastoma in chinese patients.
8572159 - Brief communication: a possible case of melorheostosis from antiquity.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ     Volume:  8     ISSN:  1020-3397     ISO Abbreviation:  East. Mediterr. Health J.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2004-08-27     Completed Date:  2004-10-14     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9608387     Medline TA:  East Mediterr Health J     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  42-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, College of Medicine, University of Baghdad, Baghdad, Iraq.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Case-Control Studies
Electrophoresis, Cellulose Acetate
Erythrocytes / enzymology
Favism / epidemiology,  genetics
Gene Frequency / genetics*
Genetic Heterogeneity
Genetic Testing
Genetic Variation / genetics*
Glucosephosphate Dehydrogenase / genetics
Glucosephosphate Dehydrogenase Deficiency / diagnosis,  epidemiology*,  genetics*
Humans
Iraq / epidemiology
Male
Middle Aged
Molecular Epidemiology
Phenotype
Polymorphism, Genetic / genetics*
Urban Health / statistics & numerical data
Chemical
Reg. No./Substance:
EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 1.1.1.49/glucose-6-phosphate dehydrogenase A-

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Risk factors associated with hospital emergency visits among asthmatic schoolboys in Saudi Arabia.
Next Document:  Rapid carrier screening using short tandem repeats in the phenylalanine hydroxylase gene.