Document Detail

Red blood cells amino-acid pattern in protein energy malnutrition and the effect of oral dosing with single amino acids.
MedLine Citation:
PMID:  6777998     Owner:  NLM     Status:  MEDLINE    
R.B.C.'s amino acid pattern was investigated in control and PEM subjects. The effect of oral dosing with cysteine, tryptophan and lysine on total amino acid nitrogen level of R.B.C.s was also studied. Results revealed that in moderate and severe kwashiorkor the total essential and non-essential R.B.C.'s amino acids were decreased. In 2nd grade marasmus the total R.B.C.'s amino acids in general showed lower values than normal. After oral administration of the tested amino acids, the transport index calculated as the level of maximum value of the total R.B.C.'s amino acids reached to the fasting level was lower in malnourished cases relative to controls except in 2nd grade marasmic cases given tryptophan or lysine. This criteria was considered to indicate lower rate of amino acid transport to R.B.C.s due to lower concentration in plasma or shift of transport mechanism from active transport to exchange diffusion.
F A el-Shobaki; N el-Shawarby; M F el-Hawary; R Sakr
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zeitschrift für Ernährungswissenschaft     Volume:  19     ISSN:  0044-264X     ISO Abbreviation:  Z Ernahrungswiss     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1981-02-24     Completed Date:  1981-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0413632     Medline TA:  Z Ernahrungswiss     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  147-53     Citation Subset:  IM    
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MeSH Terms
Amino Acids / blood*
Amino Acids, Essential / blood
Biological Transport
Child, Preschool
Cysteine / pharmacology*
Erythrocytes / metabolism*
Kwashiorkor / blood
Lysine / pharmacology*
Protein-Energy Malnutrition / blood*,  classification
Tryptophan / pharmacology*
Reg. No./Substance:
0/Amino Acids; 0/Amino Acids, Essential; 52-90-4/Cysteine; 56-87-1/Lysine; 73-22-3/Tryptophan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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