Document Detail


Red blood cell sodium-lithium countertransport in patients with essential and renal hypertension.
MedLine Citation:
PMID:  8007744     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The erythrocyte Na+/Li(+)-countertransport activity was studied in patients with essential hypertension (n = 59), chronic glomerulonephritis (n = 30), chronic pyelonephritis (n = 26), renovascular hypertension (n = 35) and pheochromocytoma (n = 3). The erythrocyte Na+/Li(+)-countertransport (SLC) activity was on average higher (p < 0.02) in the patients with essential hypertension as compared to those with secondary hypertension, although a clear distinction between both groups was not possible. After surgical treatment of the patients with atherosclerotic renal artery stenosis, fibromuscular dysplasia or pheochromocytoma, no change in erythrocyte SLC activity was observed. However, blood pressure was significantly reduced.
Authors:
V V Petrov; C G Arabidze; D O Levitsky; A O Eliseev; P J Lijnen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods and findings in experimental and clinical pharmacology     Volume:  16     ISSN:  0379-0355     ISO Abbreviation:  Methods Find Exp Clin Pharmacol     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909595     Medline TA:  Methods Find Exp Clin Pharmacol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  153-7     Citation Subset:  IM    
Affiliation:
Cardiology Research Center, Moscow, Russia.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Neoplasms / blood,  complications,  surgery
Adult
Antiporters / blood*
Arteriosclerosis / blood,  complications,  surgery
Blood Pressure / physiology
Erythrocytes / metabolism*
Female
Fibromuscular Dysplasia / blood,  surgery
Glomerulonephritis / blood,  complications
Humans
Hypertension / blood*,  physiopathology
Hypertension, Renal / blood*,  etiology,  physiopathology
Hypertension, Renovascular / blood
Lithium / blood*
Male
Pheochromocytoma / blood,  complications,  surgery
Pyelonephritis / blood,  complications
Sodium / blood*
Chemical
Reg. No./Substance:
0/Antiporters; 0/sodium-lithium countertransporter; 7439-93-2/Lithium; 7440-23-5/Sodium

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