Document Detail

Recurrent transient hyperphosphatasemia of infancy in an adult.
MedLine Citation:
PMID:  1526034     Owner:  NLM     Status:  MEDLINE    
We report a case of recurrent transient hyperphosphatasemia in a 29-year-old man with immune deficiency. He had serum alkaline phosphatase (ALP; EC activity 16.9- and 4.8-fold greater than the upper reference limit on two occasions; the activity returned to normal within 2 months on the first and within 1 month on the second. On both occasions we observed the typical electrophoretic pattern for ALP isoenzymes seen in transient hyperphosphatasemia of infancy. We noted no evidence of liver or bone disease. Recognition of the occurrence of transient hyperphosphatasemia of infancy in adults, although rare (it is the fifth case reported), seems as important as in children so that unnecessary extensive investigations are avoided.
D Onica; J Torssander; L Waldenlind
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  38     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-10-20     Completed Date:  1992-10-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1913-5     Citation Subset:  IM    
Department of Clinical Chemistry, Karolinska Institute, Stockholm, Sweden.
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MeSH Terms
Alkaline Phosphatase / blood*
Immunocompromised Host
Isoenzymes / blood*
Metabolism, Inborn Errors / blood,  diagnosis
Reg. No./Substance:
0/Isoenzymes; EC Phosphatase

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