Document Detail

Recurrent seizures in pregnancy-epilepsy or eclampsia: a diagnostic dilemma? A case report.
MedLine Citation:
PMID:  23256267     Owner:  NLM     Status:  In-Process    
Peripartum seizure is a serious disease with substantial morbidity and mortality for the mother and fetus. Among various causes of such seizures, sometimes 2 causative factors can occur, simultaneously creating a dilemma in pharmacotherapeutic management. We describe a 34-weeks-pregnant woman with a history of epilepsy (receiving antiepileptic drugs) who had eclampsia and recurrent seizures in the peripartum period. Seizure control required multiple medications, including benzodiazepine, valproate, phenytoin, and magnesium sulfate. She underwent emergent cesarean delivery under general anesthesia to rescue the baby. Blood pressure control was achieved using alpha-methyldopa, labetalol, nitroglycerine, and amlodipine. Maximum vigilance is required for such patients, and therapy needs to be titrated according to patient's response, keeping in mind its impact on the fetus.
Ravindra Pandey; Rakesh Garg; Vanlal Darlong; Jyotsna Punj; Puneet Khanna
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AANA journal     Volume:  79     ISSN:  0094-6354     ISO Abbreviation:  AANA J     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0431420     Medline TA:  AANA J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  388-90     Citation Subset:  N    
Department of Anaesthesiology and Intensive Care, All India Institute of Medical Sciences, New Delhi, India.
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