| Recurrent pregnancy loss and antiphospholipid syndrome: an overlooked association. | |
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MedLine Citation:
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PMID: 21416793 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Antiphospholipid Syndrome (APS), a thrombophilic condition, is being increasingly recognised as an important cause of recurrent pregnancy loss, preeclampsia and possible infertility. It could occur as a primary condition or it may be secondary to connective tissue diseases, infections or malignancies. Though recurrent pregnancy loss is a common feature ofAPS, there are other presentations attributable to thrombosis. The mechanism of thrombosis is still not completely understood but there are various suggested mechanisms. Presence of anti-cardiolipin antibodies (aCL) and lupus anticoagulant (LAC) are diagnostic. Management is variously with heparin, aspirin and warfarin, although other treatment modalities are being deployed. A high index of suspicion is needed for this otherwise treatable condition. Management is ideally best done by an obstetrician and a rheumatologist. |
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Authors:
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O O Adelowo; O O Adetoro |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: African journal of medicine and medical sciences Volume: 39 ISSN: 0309-3913 ISO Abbreviation: Afr J Med Med Sci Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2011-03-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7801013 Medline TA: Afr J Med Med Sci Country: Nigeria |
Other Details:
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Languages: eng Pagination: 227-31 Citation Subset: IM |
Affiliation:
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Rheumatology Unit, Department of Medicine, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. femiadelowo2003@yahoo.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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