Document Detail


Recurrent pregnancy loss and antiphospholipid syndrome: an overlooked association.
MedLine Citation:
PMID:  21416793     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Antiphospholipid Syndrome (APS), a thrombophilic condition, is being increasingly recognised as an important cause of recurrent pregnancy loss, preeclampsia and possible infertility. It could occur as a primary condition or it may be secondary to connective tissue diseases, infections or malignancies. Though recurrent pregnancy loss is a common feature ofAPS, there are other presentations attributable to thrombosis. The mechanism of thrombosis is still not completely understood but there are various suggested mechanisms. Presence of anti-cardiolipin antibodies (aCL) and lupus anticoagulant (LAC) are diagnostic. Management is variously with heparin, aspirin and warfarin, although other treatment modalities are being deployed. A high index of suspicion is needed for this otherwise treatable condition. Management is ideally best done by an obstetrician and a rheumatologist.
Authors:
O O Adelowo; O O Adetoro
Related Documents :
1420213 - Gender differences in knowledge, intentions, and behaviors concerning pregnancy and sex...
18925473 - Young women's experience of termination and miscarriage: a qualitative study.
10475503 - Matrix metalloproteinases-9 in preterm and term human parturition.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  39     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-03-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  Nigeria    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  IM    
Affiliation:
Rheumatology Unit, Department of Medicine, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. femiadelowo2003@yahoo.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Age at diagnosis of sickle cell disease in a developing country.
Next Document:  The HIV/AIDS epidemic in Nigeria: progress, problems and prospects.