Document Detail

Recurrent polyposis nasi. Documentation.
MedLine Citation:
PMID:  2772494     Owner:  NLM     Status:  MEDLINE    
After a short historical review a proposal is made for the definition of nasal polyposis. The authors studied 350 CT-scans of patients with nasal complaints. In a high percentage anatomical anomalies were observed. In 57.5% of the CT-scans sinus mucosal disease was visible. In all patients with maxillary sinus disease polyps (rounded structures) could be found; in 31% these polyps were mainly of grade 2. From a retrospective study of 111 biopsies of nasal polyposis (65 patients) it became clear that different polyps from the same patient showed substantial difference in cellular content, i.e. presence of eosinophils, neutrophils, plasma cells, glands, ducti and thickening of the basal membrane. As oral acetylsalicylic acid provocation may be hazardous in ASA-sensitive patients, the authors developed a nasal aspirin provocation test. This nasal ASA test was carried out in 10 normal test subjects, 10 patients with aspecific hyperreactivity, 10 atopic patients and 16 patients with polyposis nasi. The reproducibility of the test, however, was so poor that the nasal ASA challenge test in its present form does not appear to be of any great clinical value. Finally, the authors discuss the physiopathology of nasal polyposis.
P A Clement; P van der Veken; J Verstraelen; T Buisseret; A Cox; N Frécourt; L Kaufman; M P Derde
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rhinology. Supplement     Volume:  8     ISSN:  1013-0047     ISO Abbreviation:  Rhinol. Suppl.     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-03     Completed Date:  1989-10-03     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  9004674     Medline TA:  Rhinol Suppl     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  5-14     Citation Subset:  IM    
Dept. of O.R.L., Free University of Brussels, Belgium.
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MeSH Terms
Airway Resistance / drug effects
Aspirin / diagnostic use
Middle Aged
Nasal Polyps / etiology,  radiography*
Nasal Provocation Tests
Neoplasm Recurrence, Local / radiography*
Neoplasms, Multiple Primary / radiography
Paranasal Sinus Neoplasms / radiography
Tomography, X-Ray Computed*
Reg. No./Substance:

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