Document Detail

Recurrent pituitary ependymoma: a complex clinical problem.
MedLine Citation:
PMID:  18704689     Owner:  NLM     Status:  MEDLINE    
Ependymomas rarely arise from the region of the pituitary fossa, with only four cases previously reported in the literature. We present a complex case of a recurrent ependymoma of the parasellar region which has been difficult to clinically manage due to its tendency to recurrence. Our patient has had four operations over the last 28 years, with external beam radiotherapy, but still has residual tumor and is currently panhypopituitary and with significant visual loss. We believe there is considerable uncertainty as to the optimal management of any future progression, which seems likely, and are currently considering the use of radiosurgery with careful sparing of the optic chiasm, or possibly the chemotherapeutic agent temozolomide. Our case emphasises the recurrent nature of this rare but difficult tumor.
Rosie Belcher; Harvinder S Chahal; Jane Evanson; Farhad Afshar; Silvia Marino; Ashley B Grossman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pituitary     Volume:  13     ISSN:  1573-7403     ISO Abbreviation:  Pituitary     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-04-19     Completed Date:  2010-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9814578     Medline TA:  Pituitary     Country:  United States    
Other Details:
Languages:  eng     Pagination:  176-82     Citation Subset:  IM    
Department of Endocrinology, Barts and the London School of Medicine, London, UK.
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MeSH Terms
Ependymoma / diagnosis*,  radiotherapy
Magnetic Resonance Imaging
Neoplasm Recurrence, Local / diagnosis*,  radiotherapy
Pituitary Neoplasms / diagnosis*,  radiotherapy

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