| Recurrent lymphomatoid papulosis associated with nephrotic syndrome. An occurrence of uncertain origin. | |
| | |
MedLine Citation:
|
PMID: 18026996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report on a 10-year-old child with nephrotic syndrome who developed recurrent lymphomatoid papulosis (LYP) 60 months after the first episode of proteinuria. LYP appeared when the child was taking low-dose cyclosporin and disappeared after the drug was replaced by prednisone at doses utilized for nephrotic syndrome (2 mg/kg). During the tapering of steroids, when the child was treated with low-dose prednisone (0.2 mg/kg), both LYP and nephrotic syndrome started again and required the reintroduction of prednisone to restore a normal clinical situation. This is the first case of LYP occurring in concomitance and synchronous with nephrotic syndrome. LYP was unrelated to cyclosporin (second episode after its withdrawn) but preceded the recurrence of proteinuria, suggesting a relationship with the disease activity. Even though the etiology of LYP is, in this case, uncertain, it should be considered as a clinical association of nephrotic syndrome in children and also included among potential triggers of the disease. |
| | |
Authors:
|
Gian Marco Ghiggeri; Dario Bleid; Alberto Garaventa; Cristina Coccia; Claudio Gambini; Gianluca Caridi; Francesco Perfumo |
Related Documents
:
|
10444806 - Nephrotic syndrome and acute interstitial nephritis associated with the use of diclofenac. 926466 - Anal complication in behçet's syndrome. 8182716 - Microcephaly and congenital nephrotic syndrome owing to diffuse mesangial sclerosis: an... 19652856 - Primary lymphoedema at an unusual location triggered by nephrotic syndrome. 19886366 - Cornelia de lange syndrome: description of the orofacial features and case report. 16691586 - Periventricular nodular heterotopia and williams syndrome. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2007-11-20 |
Journal Detail:
|
Title: Pediatric nephrology (Berlin, Germany) Volume: 24 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2009 Jan |
Date Detail:
|
Created Date: 2009-02-04 Completed Date: 2009-04-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: Germany |
Other Details:
|
Languages: eng Pagination: 189-92 Citation Subset: IM |
Affiliation:
|
Laboratory on Pathophysiology of Uremia, G. Gaslini Children Hospital, Largo G. Gaslini 5, 16148, Genova, Italy. labnefro@ospedale-gaslini.ge.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Cyclosporine / therapeutic use Dose-Response Relationship, Drug Glucocorticoids / therapeutic use Humans Immunosuppressive Agents / therapeutic use Lymphomatoid Papulosis / complications, pathology* Male Nephrotic Syndrome / complications, drug therapy, pathology* Prednisone / therapeutic use Proteinuria / drug therapy, etiology, pathology Recurrence |
| Chemical | |
Reg. No./Substance:
|
0/Glucocorticoids; 0/Immunosuppressive Agents; 53-03-2/Prednisone; 59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ascorbate peroxidase gene family in tomato: its identification and characterization.
Next Document: Dimercaptosuccinic acid (DMSA) renal scan in the evaluation of hypertension in children.