Document Detail

Recurrent hemoptysis: an emerging life-threatening complication in idiopathic pulmonary arterial hypertension.
MedLine Citation:
PMID:  21362657     Owner:  NLM     Status:  In-Data-Review    
Hemoptysis is a rarely reported complication of idiopathic pulmonary arterial hypertension (IPAH). We present the case of a 27-year-old woman with IPAH, who suffered from recurrent hemoptysis and who was treated with sitaxsentan and treprostinil and remained stable in World Health Organization functional class II. During several episodes of active hemoptysis, the patient underwent bronchial artery embolization (BAE), always with good immediate results. She developed severe respiratory insufficiency and died of electromechanical dissociation 2 days after another episode, despite effective bleeding control. Recurrent hemoptysis in patients with IPAH emerges as a potential indication for urgent placement on the lung transplant list, independent from the classic prognostic factors of functional class and indices of right-sided ventricular function. Repeated BAE should not be considered as a definitive treatment in patients with pulmonary arterial hypertension with recurrent bleeding, although it may help in bridging patients to lung transplant.
Joanna Zylkowska; Marcin Kurzyna; Radoslaw Pietura; Anna Fijalkowska; Michal Florczyk; Cezary Czajka; Adam Torbicki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  139     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  690-3     Citation Subset:  AIM; IM    
Department of Chest Medicine, Institute of Tuberculosis and Lung Diseases, 1, Plocka 26, 01-138 Warsaw, Poland.
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