| Recurrent erythema multiforme triggered by progesterone sensitivity. | |
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MedLine Citation:
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PMID: 20849459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Determining the underlying etiology of recurrent erythema multiforme (EM) can be a difficult endeavor. Although infection with herpes simplex virus (HSV) has been implicated in some cases, the precise trigger of a given patient's recurrent EM often remains elusive. We discuss the case of a woman with a recurrent blistering eruption that was clinically and histopathologically consistent with EM. An investigation into the etiology of the patient's EM suggested that HSV was not the causative factor but instead pointed toward a hormonal influence that we interpret as autoimmune progesterone dermatitis (APD). This case is presented to highlight the importance of considering hormonal triggers in women with recurrent EM that consistently flares during the luteal phase of the menstrual cycle, the point at which serum progesterone levels peak. A brief review of the literature regarding the diagnosis, histopathology, etiology and treatment of APD is further provided. |
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Authors:
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Teresa J Nasabzadeh; Catherine M Stefanato; John E Doole; Arash Radfar; Jag Bhawan; Suraj Venna |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of cutaneous pathology Volume: 37 ISSN: 1600-0560 ISO Abbreviation: J. Cutan. Pathol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-09-20 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0425124 Medline TA: J Cutan Pathol Country: Denmark |
Other Details:
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Languages: eng Pagination: 1164-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 John Wiley & Sons A/S. |
Affiliation:
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Washington Hospital Center, Department of Internal Medicine-Dermatology, 110 Irving Street NW, Washington DC 20010, USA. Teresa.J.Nasabzadeh@medstar.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
/
complications,
pathology Erythema Multiforme / etiology, pathology* Female Humans Progesterone / adverse effects, diagnostic use Young Adult |
| Chemical | |
Reg. No./Substance:
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57-83-0/Progesterone |
| Comments/Corrections | |
Comment In:
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J Cutan Pathol. 2010 Nov;37(11):1130-1
[PMID:
20849455
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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