| Recurrent endometrial cancer: a retrospective study. | |
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MedLine Citation:
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PMID: 16460871 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The value of follow-up after treatment for endometrial cancer will be discussed. STUDY DESIGN: We evaluated our clinical experience, including mode of detection, of patients with recurrent endometrial cancer treated in the Erasmus Medical Centre in Rotterdam over a 20-year period. Clinical data and histopathological features from 64 patients were analyzed. Survival was analyzed with a Kaplan-Meier curve. RESULTS: Twenty-two patients had a local recurrence, 30 had a distant recurrence and 12 had simultaneous local and distant recurrent disease. Ninety-five percent of the local recurrences and 67% of the distant recurrences were detected within three years. Twenty-seven patients had a screen-detected recurrence, 34 had an interval screening recurrence and two had a chance finding recurrence. The overall survival rate at two years was 70% and at five years 53%. Patients with a screen-detected recurrence had a 5-year survival rate of 62%, while patients with interval screening and chance finding recurrences had a 5-year survival rate of 47%. CONCLUSION: A follow-up program in the first three years after primary treatment of endometrial cancer is useful in detecting recurrent disease. We have no reason to use a different program of follow-up in patients with low risk primary disease. |
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Authors:
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F H van Wijk; F J Huikeshoven; L Abdulkadir; P C Ewing; C W Burger |
Publication Detail:
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Type: Journal Article Date: 2006-02-03 |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 130 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2006-12-22 Completed Date: 2007-04-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: Ireland |
Other Details:
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Languages: eng Pagination: 114-20 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecological Diseases, Erasmus Medical Centre, Rotterdam, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Carcinoma, Adenosquamous / epidemiology*, therapy Cystadenocarcinoma, Serous / epidemiology*, therapy Endometrial Neoplasms / epidemiology*, pathology*, therapy Female Humans Kaplan-Meiers Estimate Middle Aged Neoplasm Metastasis Neoplasm Recurrence, Local / diagnosis, pathology*, therapy Neoplasm Staging Netherlands / epidemiology Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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