Document Detail


Recurrent endometrial cancer: a retrospective study.
MedLine Citation:
PMID:  16460871     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The value of follow-up after treatment for endometrial cancer will be discussed. STUDY DESIGN: We evaluated our clinical experience, including mode of detection, of patients with recurrent endometrial cancer treated in the Erasmus Medical Centre in Rotterdam over a 20-year period. Clinical data and histopathological features from 64 patients were analyzed. Survival was analyzed with a Kaplan-Meier curve. RESULTS: Twenty-two patients had a local recurrence, 30 had a distant recurrence and 12 had simultaneous local and distant recurrent disease. Ninety-five percent of the local recurrences and 67% of the distant recurrences were detected within three years. Twenty-seven patients had a screen-detected recurrence, 34 had an interval screening recurrence and two had a chance finding recurrence. The overall survival rate at two years was 70% and at five years 53%. Patients with a screen-detected recurrence had a 5-year survival rate of 62%, while patients with interval screening and chance finding recurrences had a 5-year survival rate of 47%. CONCLUSION: A follow-up program in the first three years after primary treatment of endometrial cancer is useful in detecting recurrent disease. We have no reason to use a different program of follow-up in patients with low risk primary disease.
Authors:
F H van Wijk; F J Huikeshoven; L Abdulkadir; P C Ewing; C W Burger
Publication Detail:
Type:  Journal Article     Date:  2006-02-03
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  130     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-22     Completed Date:  2007-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  114-20     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecological Diseases, Erasmus Medical Centre, Rotterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Carcinoma, Adenosquamous / epidemiology*,  therapy
Cystadenocarcinoma, Serous / epidemiology*,  therapy
Endometrial Neoplasms / epidemiology*,  pathology*,  therapy
Female
Humans
Kaplan-Meiers Estimate
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local / diagnosis,  pathology*,  therapy
Neoplasm Staging
Netherlands / epidemiology
Retrospective Studies

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