| Recurrent differentiation syndrome or septic shock? Unresolved dilemma in a patient with acute promyelocytic leukemia. | |
| | |
MedLine Citation:
|
PMID: 20204541 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Differentiation syndrome (DS) is a life-threatening complication observed in patients with acute promyelocytic leukemia (APL) receiving induction therapy with all-trans-retinoic acid (ATRA). A bimodal incidence of DS has been observed, with a majority of cases occurring during the first week of ATRA treatment ("early" DS), but a substantial number of cases occurring during the third or even fourth week of ATRA treatment ("late" DS). However, to our knowledge occurrence of both early and late DS in the same patient has not been reported. We report an APL patient treated with the AIDA regimen, who experienced both early and late DS, a situation where differential diagnosis was difficult. |
| | |
Authors:
|
Ramzi Jeddi; Hela Ghédira; Ramzi Ben Amor; Samia Menif; Zaher Belhadjali; Balkis Meddeb |
Publication Detail:
|
Type: Journal Article Date: 2010-03-05 |
Journal Detail:
|
Title: Medical oncology (Northwood, London, England) Volume: 28 ISSN: 1559-131X ISO Abbreviation: Med. Oncol. Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-02-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9435512 Medline TA: Med Oncol Country: United States |
Other Details:
|
Languages: eng Pagination: 279-81 Citation Subset: IM |
Affiliation:
|
Hematology Department, Aziza Othmana University Hospital, Tunis, Tunisia, ramzi.jed@voila.fr. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hypoglycemia, an atypical early sign of hepatocellular carcinoma.
Next Document: Zoledronic acid and clodronate in the treatment of malignant bone metastases with hypercalcaemia; ef...