| Recurrent dermatofibrosarcoma protuberans with myxoid and fibrosarcomatous changes paralleled by loss of CD34 expression. | |
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MedLine Citation:
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PMID: 8537553 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 38-year-old woman complained of recurrent nodules on her anterior chest wall. She noticed the first nodule at the age of 12 and has since undergone surgical removal a total of 31 times. Finally, wide resection of parts of the rib cartilage and sternum and chest wall reconstruction were required. Histopathological examination of a series of surgical specimens were reevaluated. Immunohistochemical staining of the tumors by anti-CD34 antibody provided a definite diagnosis of dermatofibrosarcoma protuberans (DFSP). A noteworthy result was that her DFSP did not always express CD34; the recurrent tumors with myxoid and fibrosarcomatous changes lost their CD34 expression. |
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Authors:
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N Sato; K Kimura; Y Tomita |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 22 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 1995 Sep |
Date Detail:
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Created Date: 1996-02-07 Completed Date: 1996-02-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 665-72 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Akita University School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antigens, CD34 / analysis Biopsy Dermatofibrosarcoma / immunology, pathology*, surgery Female Humans Immunohistochemistry Neoplasm Recurrence, Local / immunology, pathology*, surgery Skin Neoplasms / immunology, pathology*, surgery |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD34 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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