Document Detail

Recurrent cerebral embolism in cardiac amyloidosis.
MedLine Citation:
PMID:  3771004     Owner:  NLM     Status:  MEDLINE    
Cardiac involvement is common in systemic amyloidosis. The most frequent cardiovascular manifestations are congestive heart failure and arrhythmias. Embolic complications often occur after the onset of these symptoms. We report a 46-year-old woman with systemic amyloidosis, who sustained two middle cerebral artery strokes and shortly after developed symptoms of cardiac and renal failure with a rapid fatal course. Postmortem findings revealed mural thrombi in the left atrium as the source of embolism to the brain, to the spleen, and to the left kidney. As no evidence of congestive heart failure or arrhythmias was found in the beginning, the mechanism of mural thrombosis was probably an alteration in the thrombogenicity of the endocardium itself.
H E Bøtker; O B Rasmussen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  13     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-12-12     Completed Date:  1986-12-12     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  81-3     Citation Subset:  IM    
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MeSH Terms
Amyloidosis / complications*
Cardiomyopathies / complications*
Intracranial Embolism and Thrombosis / etiology*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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