Document Detail

Recurrent cardiogenic shock caused by dynamic mitral regurgitation in a patient with hypertrophic obstructive cardiomyopathy: a case report.
MedLine Citation:
PMID:  15801278     Owner:  NLM     Status:  MEDLINE    
A 68-year-old man with hypertrophic obstructive cardiomyopathy developed recurrent cardiogenic shock due to dynamic mitral regurgitation. The pressure gradient in the left ventricular outflow tract under medication was 30 mmHg, and he complained of no symptom. He developed shock with dyspnea suddenly after bathing and defecation. Echocardiography and left ventriculography revealed massive mitral regurgitation and mild increment of pressure gradient in the left ventricular outflow tract (50 mmHg). He underwent successful mitral valve replacement following treatment with beta-blocker under intraaortic balloon pumping support. This case illustrates that exacerbation of the systolic anterior motion of the mitral anterior leaflet can cause dynamic severe mitral regurgitation with 'mild' increment of pressure gradient in the left ventricular outflow tract, resulting in cardiogenic shock with severe lung edema.
Tomohiro Nakamura; Yoshitaka Sugawara; Takeshi Ishida; Nahoko Ikeda; Hiroshi Funayama; Takanori Yasu; Norifumi Kubo; Mikihisa Fujii; Masanobu Kawakami; Shuichiro Takanashi; Muneyasu Saito
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  45     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-04-01     Completed Date:  2005-04-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  129-33     Citation Subset:  IM    
Department of Integrated Medicine 1, Omiya Medical Center, Jichi Medical School, Saitama.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Cardiomyopathy, Hypertrophic / complications*,  therapy
Combined Modality Therapy
Heart Valve Prosthesis Implantation
Intra-Aortic Balloon Pumping*
Mitral Valve / surgery
Mitral Valve Insufficiency / complications*,  surgery
Propranolol / therapeutic use
Shock, Cardiogenic / etiology*,  therapy
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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