| Recurrent blocked duct(s) in a mother with immunoglobulin A deficiency. | |
| | |
MedLine Citation:
|
PMID: 19086829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Abstract Secretory immunoglobulin A (sIgA) is the dominant immunoglobulin in human milk, and apart from the obvious contribution it makes towards the protection of the infant, sIgA may also form an important part of the defense of the mammary gland. This report involves a mother (M8) who participated in a research study investigating the relationships between symptoms and changes in the physiology of the lactating breast during mastitis. Breastmilk samples were collected on Days 14, 30, 60, and 90 postpartum, to establish the normal reference range of biochemical markers, and during periods of breast inflammation. M8 experienced seven episodes of blocked duct(s) during the first 19 weeks, five of which occurred within the 90-day reference sample collection period. On analysis, it was found there was no detectable sIgA present in her milk samples. Medical referral and further testing resulted in a diagnosis of selective IgA deficiency, of which the mother had not been previously aware. M8 showed little variation in her milk composition even when suffering with blocked duct(s), although there was an increase in the concentration of lactoferrin in both breasts at reference collection days 14-90. Lactoferrin concentration was also unusually high at Day 14 (15 g/L) in the left breast and continued to be increased in this breast until Day 60. The absence of sIgA in this mother's breastmilk may have been a contributing factor in her experiencing recurrent blocked ducts. |
| | |
Authors:
|
C M Fetherston; C T Lai; P E Hartmann |
Related Documents
:
|
1459679 - Infant feeding practices in rural bangladesh. 8051529 - Lactation amenorrhea in saudi women. 19169349 - Rickets of prematurity- a case report. 2515939 - The effects of a progestin-only oral contraceptive (levonorgestrel 0.03 mg) on breast-f... 3500939 - Feeding and nutritional status among infants in basrah city, iraq: a cross-sectional st... 73009 - Infant feeding and subcutaneous fat at birth and at one year. 22415299 - Catch up growth in low birth weight infants: striking a healthy balance. 15296559 - Modelling consultation rates in infancy: influence of maternal and infant characteristi... 22385309 - Maternal sensitivity to infants in various settings predicts harsh discipline in toddle... |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine Volume: 3 ISSN: 1556-8342 ISO Abbreviation: - Publication Date: 2008 Dec |
Date Detail:
|
Created Date: 2008-12-17 Completed Date: 2009-01-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101260777 Medline TA: Breastfeed Med Country: United States |
Other Details:
|
Languages: eng Pagination: 261-5 Citation Subset: IM |
Affiliation:
|
School of Nursing, Murdoch University, Mandurah, WA, Australia. C.Fetherston@murdoch.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Biological Markers Breast / pathology*, secretion Female Humans IgA Deficiency / complications* Immunoglobulin A, Secretory / metabolism* Lactation / metabolism Lactoferrin / metabolism Mastitis / etiology, metabolism*, pathology Milk, Human / chemistry*, secretion |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Immunoglobulin A, Secretory; 0/Lactoferrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The heart of the matter on breastmilk and environmental chemicals: essential points for healthcare p...
Next Document: Psychological treatment of anxiety: the evolution of behavior therapy and cognitive behavior therapy...