Document Detail


Recurrent seizures and serotonin syndrome following "2C-I" ingestion.
MedLine Citation:
PMID:  23378129     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The phenethylamines, including 2, 5 dimethoxy-4-iodophenethylamine, commonly referred to as 2C-I, have recently emerged as a new class of designer drugs. Cases of toxicity from these drugs are not well described in the literature. This case report describes a 19 year-old male who insufflated 2C-I. Following the ingestion, the patient developed recurrent seizures, and was taken to the emergency department, where he was noted to be hyperadrenergic and had recurrent seizures. The patient was diagnosed with serotonin syndrome and experienced prolonged respiratory failure, although he ultimately made a full recovery. Comprehensive drug testing revealed the presence of 2C-I. The pharmacologic properties of 2C-I are also discussed.
Authors:
Adam Bosak; Frank LoVecchio; Michael Levine
Related Documents :
24147649 - Bgg492 (selurampanel), an ampa/kainate receptor antagonist drug for epilepsy.
19818789 - Sex differences and ovarian hormones in animal models of drug dependence.
15084439 - Hippocampal memory system function and the regulation of cocaine self-administration be...
6629569 - Psychological aspects of drug-taking behavior.
12527019 - Importance of nonpharmacological factors in nicotine self-administration.
7000029 - Double-blind evaluation of reinforcing and anorectic actions of weight control medicati...
10333319 - Bisquinoline antimalarials: their role in malaria chemotherapy.
10417009 - Pharmaceutical use by u.s. astronauts on space shuttle missions.
10725309 - Studies on the cytochrome p450 (cyp)-mediated metabolic properties of miocamycin: evalu...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical toxicology : official journal of the American College of Medical Toxicology     Volume:  9     ISSN:  1937-6995     ISO Abbreviation:  J Med Toxicol     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-20     Completed Date:  2013-12-17     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  101284598     Medline TA:  J Med Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  196-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Designer Drugs / administration & dosage,  analysis,  toxicity*
Dimethoxyphenylethylamine / administration & dosage,  analogs & derivatives*,  toxicity,  urine
Emergency Service, Hospital
Humans
Insufflation
Male
Phenethylamines / administration & dosage,  toxicity*,  urine
Respiratory Insufficiency / etiology
Seizures / etiology*
Serotonin Syndrome / etiology*
Substance-Related Disorders / physiopathology*,  urine
Treatment Outcome
Young Adult
Chemical
Reg. No./Substance:
0/4-iodo-2,5-dimethoxy-beta-phenethylamine; 0/Designer Drugs; 0/Dimethoxyphenylethylamine; 0/Phenethylamines
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Michrochip chromatography using an open-tubular microchannel and a ternary water-ACN-ethyl acetate m...
Next Document:  Robust object-based encoding in visual working memory.