Document Detail


Recurrent D-lactic acidosis in a child with short bowel syndrome.
MedLine Citation:
PMID:  15927940     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
D-lactic acidosis is a rare complication in children with short bowel syndrome. It results from fermentation of dietary carbohydrate by luminal bacteria in the small bowel caused by bacterial overgrowth. We present the case of a 14-year-old boy who had been diagnosed with short bowel syndrome from surgical treatment of midgut volvulus five years previously. His nutritional status was maintained by total parenteral nutrition and enteral feeding as tolerated. During hospitalization, episodic confusion and hyperpnea developed. The investigation showed severe metabolic acidosis with serum bicarbonate of 9 mmol/L and a wide anion gap. The serum D-lactic acid was 11.21 mmol/L. There was no evidence of renal or hepatic failure. Therefore, D-lactic acidosis from enteral carbohydrate overload was diagnosed. The treatment was correction of metabolic acidosis by sodium bicarbonate infusion and carbohydrate restriction. The results of the therapy were satisfactory. Early detection and appropriate treatment is necessary to avoid morbidity and mortality following this complication of short bowel syndrome.
Authors:
Maneerat Puwanant; Ladda Mo-Suwan; Sakda Patrapinyokul
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Asia Pacific journal of clinical nutrition     Volume:  14     ISSN:  0964-7058     ISO Abbreviation:  Asia Pac J Clin Nutr     Publication Date:  2005  
Date Detail:
Created Date:  2005-06-01     Completed Date:  2005-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440304     Medline TA:  Asia Pac J Clin Nutr     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  195-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat-Yai, Songkhla, Thailand. mpuwanant@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Acidosis, Lactic / etiology*,  therapy
Adolescent
Bicarbonates / blood,  metabolism*,  therapeutic use
Dietary Carbohydrates / administration & dosage*,  metabolism
Humans
Male
Parenteral Nutrition, Total
Protein-Energy Malnutrition / etiology,  therapy
Recurrence
Short Bowel Syndrome / complications*,  therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Dietary Carbohydrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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