| Recurrent Cushing's syndrome after adrenal autotransplantation. | |
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MedLine Citation:
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PMID: 19885999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Adrenalectomy with adrenal autotransplantation used to be performed frequently for Cushing's disease in the past because of the limitations of conventional radiological techniques and the lack of adequate neurosurgical techniques. Today, however, bilateral adrenalectomy may be still required for selective patients with Cushing's syndrome when partial hypophysectomy has failed to control hypercortisolism or the source for ectopic ACTH syndrome could not be determined. Here, we report a case of recurrent Cushing's syndrome due to a pituitary adenoma, who was treated with bilateral adrenalectomy and autotransplantation for her Cushing's syndrome. Having determined pituitary adenoma as the cause of recurrent Cushing's syndrome after endocrinological investigations and imaging, we were able to treat the patient with transsphenoidal adenomectomy. We suggest that transsphenoidal resection of the adenoma rather than excision of the autotransplants and adrenal remnants should be the preferred treatment method for recurrent Cushing's disease. |
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Authors:
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S Yesil; T Demir; B Akinci; O Ozdogan; N Gazioglu; H Hatemi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association Volume: 117 ISSN: 1439-3646 ISO Abbreviation: Exp. Clin. Endocrinol. Diabetes Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-11-02 Completed Date: 2010-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9505926 Medline TA: Exp Clin Endocrinol Diabetes Country: Germany |
Other Details:
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Languages: eng Pagination: 470-2 Citation Subset: IM |
Affiliation:
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Division of Endocrinology and Metabolism, Department of Internal Medicine, Dokuz Eylul University, 35340 Izmir, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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ACTH-Secreting Pituitary Adenoma
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surgery* Adenoma / surgery* Adrenalectomy Adrenocorticotropic Hormone / blood Cushing Syndrome / surgery* Female Humans Hydrocortisone / blood Middle Aged Pituitary ACTH Hypersecretion / surgery* Recurrence Transplantation, Autologous Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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