| Recurrence of vulvovaginal candidosis during pregnancy. Comparison of miconazole vs nystatin treatment. | |
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MedLine Citation:
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PMID: 787858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The efficacy of miconazole and nystatin in the treatment of vulvovaginal candidosis was compared in a multicenter trial involving 94 pregnant patients. All patients had subjective complaints and were mycologically positive. Miconazole 2% vaginal cream was applied once daily for at least 10 days by 45 patients, whereas the 49 others received nystatin tablets for intravaginal application during 7 to 9 days. At the first examination following treatment, the cure rate with miconazole was 83% and with nystatin 68%. Follow-up examinations revealed a significantly lower recurrence rate in the miconazole-treated group. No important adverse experiences were noted. |
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Authors:
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H C Wallenburg; J W Wladimiroff |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 48 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1976 Oct |
Date Detail:
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Created Date: 1976-12-01 Completed Date: 1976-12-01 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 491-4 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Candida / isolation & purification Candidiasis, Vulvovaginal / drug therapy*, microbiology Clinical Trials as Topic Drug Evaluation Female Humans Imidazoles / therapeutic use* Miconazole / therapeutic use* Nystatin / therapeutic use* Pregnancy Pregnancy Complications, Infectious / drug therapy* Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Imidazoles; 1400-61-9/Nystatin; 22916-47-8/Miconazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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