Document Detail

Recurrence of secondary angiosarcoma in a patient with post-radiated breast for breast cancer.
MedLine Citation:
PMID:  18305948     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Angiosarcoma of the breast is a rare finding. Two different subtypes of angiosarcomas have been described: (a) the Stewart-Treves syndrome and (b) the cutaneous post-radiation angiosarcoma. We report a case where both types of angiosarcoma occurred. CASE REPORT: At first, an angiosarcoma affecting parenchyma of the breast was observed after radiotherapy following breast conserving therapy and a history of lymphoedema of the radiated area. Additionally, a subsequent local recurrence of the angiosarcoma of the skin after mastectomy and complete resection of the primary angiosarcoma was diagnosed. DISCUSSION: This case is distinguished by a short latency period after primary therapy (less than 4 years) and a rapid recurrence after complete resection (14 weeks). Patients should be pointed to this possible complication of radiotherapy and transferred to seek medical advice immediately in case of skin lesion in the irradiated area: even many years after radiotherapy. Additionally, every oncologist should be aware of this rare complication as quick diagnosis and prompt surgical treatment is indispensable due to the aggressive entity of angiosarcoma.
Thomas Kunkel; Ioannis Mylonas; Doris Mayr; Klaus Friese; Harald L Sommer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-02-28
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  278     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-09-08     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  497-501     Citation Subset:  IM    
First Department of Obstetrics and Gynecology, Ludwig-Maximilians-University Munich, Maistrasse 11, Munich, Germany.
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MeSH Terms
Breast Neoplasms / pathology,  radiotherapy,  therapy*
Chemotherapy, Adjuvant
Hemangiosarcoma / radiotherapy,  secondary,  therapy*
Middle Aged
Neoplasm Recurrence, Local / pathology,  therapy*
Radiotherapy, Adjuvant
Skin Neoplasms / secondary,  therapy*
Time Factors

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