Document Detail


Recurrence risks of hypertensive diseases in pregnancy after HELLP syndrome.
MedLine Citation:
PMID:  21809897     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Aim: To determine the recurrence risk for hypertensive diseases in pregnancy after HELLP (Hemolysis Elevated Liver enzymes and Low Platelets) syndrome in a first pregnancy. Methods: The study was designed as a cohort study investigating 148 Caucasian primiparae with a diagnosis of HELLP syndrome in a first pregnancy and at least one subsequent pregnancy conducted beyond the 24(th) gestational week. Diagnoses were verified by reviewing medical records and classified according to ISSHP (International Society for the Study of Hypertension in Pregnancy) criteria. The recurrence risk of HELLP syndrome or other hypertensive disorders in the subsequent pregnancy was calculated with regard to disease severity in the index pregnancy. Results: Among 148 pregnancies subsequent to HELLP syndrome, 56.1% of the women were normotensive. The recurrence rate was 12.8% for HELLP syndrome, 16.2% for pre-eclampsia, and 14.2% for gestational hypertension only. Women with HELLP syndrome ≤32 gestational weeks tended to show a greater risk of complicated subsequent pregnancies compared to women presenting with HELLP after 32 gestational weeks. Conclusions: Women with a diagnosis of HELLP syndrome are at a strongly increased risk of recurrent HELLP syndrome, pre-eclampsia or gestational hypertension, however, currently no clinical or laboratory parameters allow the prediction of recurrence risk in any individual case.
Authors:
Brigitte Leeners; Peruka M Neumaier-Wagner; Sabine Kuse; Sabine Mütze; Sabine Rudnik-Schöneborn; Klaus Zerres; Werner Rath
Related Documents :
7651657 - Transplacental needle passage in early amniocentesis and pregnancy loss.
18573697 - New strategy for the prenatal detection/exclusion of paternal cystic fibrosis mutations...
23433517 - Oocyte in vitro maturation in normo-ovulatory women.
7707697 - Pre- and postnatal diagnosis of succinic semialdehyde dehydrogenase deficiency using en...
21395907 - Decreased fetal movement prompts investigation of prenatal/neonatal nemaline myopathy: ...
24164677 - Safety of cosmetic dermatologic procedures during pregnancy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-2
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  -     ISSN:  1619-3997     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynecology, Aachen University (RWTH), Aachen, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Nomogram of fetal upper arm volume by three-dimensional ultrasound using extended imaging virtual or...
Next Document:  Influence of both a static magnetic field and penetratin on magnetic nanoparticle delivery into fibr...