Document Detail

Recurrence of in-stent restenosis in cardiac allograft vasculopathy following implantation of a sirolimus-eluting stent.
MedLine Citation:
PMID:  16101733     Owner:  NLM     Status:  MEDLINE    
Coronary lesions in patients with advanced cardiac allograft vasculopathy (CAV) are frequently treated with percutaneous coronary intervention. Despite high primary success rates, long-term outcome is significantly impaired by a high incidence of restenosis. In nontransplanted patients, the use of drug-eluting stents (DES) significantly decreases the rate of coronary in-stent restenosis. We report a case treated for cardiac allograft coronary in-stent restenosis with a sirolimus-eluting stent presenting with recurrent in-stent restenosis at follow up. However, the pattern of in-stent restenosis changed from diffuse proliferative disease in the bare-metal stent to a focal pattern in the sirolimus-eluting stent concordant with observations in nontransplanted patients. This case highlights the need for further studies addressing the effect of DES for the prevention of restenosis both in de novo as well as in-stent restenotic lesions in patients with CAV.
Rainer Wessely; Jürgen Pache; Albert Schömig
Related Documents :
15725063 - Intracoronary brachytherapy--clinical state and pathophysiological considerations.
10973013 - Long-term outcomes of minor plaque prolapsed within stents documented with intravascula...
22304853 - Assessment of ventricular contractility and ventricular-arterial coupling with a model-...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Transplant international : official journal of the European Society for Organ Transplantation     Volume:  18     ISSN:  0934-0874     ISO Abbreviation:  Transpl. Int.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-08-16     Completed Date:  2005-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908516     Medline TA:  Transpl Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1113-5     Citation Subset:  IM    
Deutsches Herzzentrum and 1. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität, Munich, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Restenosis / etiology*
Heart Transplantation / adverse effects*
Middle Aged
Sirolimus / administration & dosage*
Transplantation, Homologous
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Donor transmitted anaplastic carcinoma in a kidney-transplant recipient.
Next Document:  Transient maternal hypothyroxinemia at onset of corticogenesis alters tangential migration of medial...