| Recurrence of duodenal ulcer pain after treatment with cimetidine for four and eight weeks. | |
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MedLine Citation:
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PMID: 6991375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This double-blind controlled trial compares the relapse rate in 19 duodenal ulcer patients who received cimetidine for eight weeks with that in 19 patients who received cimetidine for four weeks and inactive tablets for four weeks. Only patients who became symptom-free during the initial four weeks' treatment with cimetidine were included. The median period of remission after withdrawal of cimetidine was 50 days in patients treated with cimetidine for eight weeks and 76 days in patients treated with cimetidine for four weeks (P greater than 0.10). Six months after withdrawal of cimetidine 15 relapses had occurred in both groups. It is concluded that patients who become symptom-free during four weeks' cimetidine treatment do not benefit by continuation of treatment for another four weeks. |
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Authors:
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S J Rune; J Greibe; K M Møllman; J R Madsen; I Rahbek; L Willumsen; H R Wulff |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Gut Volume: 21 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1980 Feb |
Date Detail:
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Created Date: 1980-08-28 Completed Date: 1980-08-28 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 151-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cimetidine / therapeutic use* Clinical Trials as Topic Double-Blind Method Duodenal Ulcer / drug therapy* Female Guanidines / therapeutic use* Humans Male Middle Aged Recurrence Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Guanidines; 51481-61-9/Cimetidine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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