| Recurrence of dense deposits in transplanted kidneys: I. Sequential survey of the lesions. | |
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MedLine Citation:
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PMID: 390215 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serial specimens from transplanted kidneys were obtained in 11 patients with dense deposit disease (DDD). The recurrence of DDD was obvious in 9 patients and appeared very early after grafting. Three different types of evolution of the lesions were observed. In 4 patients no modification of the lesions occurred with time, and in 2 of them the dense alteration alone persisted without any other glomerular changes. In 3 patients a progression of the lesions was observed, whereas a regression occurred in 1 other patient. From these observations the following sequence of the morphologic changes can be proposed: the dense alteration appears first and constitutes the specific marker of that disease; the C3 deposition in the kidney occurs later following the appearance of the dense lesion. |
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Authors:
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D Droz; B Nabarra; L H Noel; J Leibowitch; J Crosnier |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Kidney international Volume: 15 ISSN: 0085-2538 ISO Abbreviation: Kidney Int. Publication Date: 1979 Apr |
Date Detail:
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Created Date: 1980-02-26 Completed Date: 1980-02-26 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0323470 Medline TA: Kidney Int Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 386-95 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Basement Membrane
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pathology,
ultrastructure Biopsy Complement C3 / immunology Fluorescent Antibody Technique Histocytochemistry Humans Kidney / pathology, ultrastructure Kidney Diseases / pathology, surgery* Kidney Glomerulus / immunology, pathology, ultrastructure Kidney Transplantation* Microscopy, Electron Recurrence Time Factors Transplantation, Homologous |
| Chemical | |
Reg. No./Substance:
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0/Complement C3 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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