| Recurrence of Cushing's disease after long-term remission due to pituitary apoplexy. | |
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MedLine Citation:
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PMID: 11228056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We encountered a case with long-term remission of Cushing's disease due to pituitary apoplexy. The apoplexy of pituitary adenoma secreting adrenocorticotropin hormone was diagnosed by successive and timely magnetic resonance imaging when the symptoms of the patient were not yet severe and anterior pituitary dysfunction was only a transient reduction of growth hormone secretion. Seven years after the first episode of pituitary apoplexy, hypercorticism recurred, and pituitary magnetic resonance imaging showed a regrowth of the pituitary adenoma. A spontaneous remission of Cushing's disease without significant visual, neurologic or hormonal defects seems to be a much more common phenomenon than has been previously suggested. Cases with relapse after spontaneous remission of Cushing's disease are rare and the duration of remission in previous reports was within 5 years. We observed such a patient with a 7 year-remission caused by pituitary apoplexy. We consider that a careful long-term follow-up is required for patients with Cushing's disease whose remission was due to pituitary apoplexy. |
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Authors:
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Y Kamiya; Y Jin-No; K Tomita; T Suzuki; K Ban; N Sugiyama; M Mase; N Sakuma; G Kimura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Endocrine journal Volume: 47 ISSN: 0918-8959 ISO Abbreviation: Endocr. J. Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2001-02-28 Completed Date: 2001-05-31 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9313485 Medline TA: Endocr J Country: Japan |
Other Details:
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Languages: eng Pagination: 793-7 Citation Subset: IM |
Affiliation:
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Third Department of Internal Medicine, Nagoya City University Medical School, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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complications,
secretion Adrenocorticotropic Hormone / secretion Adult Cushing Syndrome / complications*, diagnosis Dexamethasone / diagnostic use Female Follicle Stimulating Hormone / secretion Gonadotropin-Releasing Hormone / diagnostic use Human Growth Hormone / secretion Humans Hydrocortisone / blood, urine Insulin / diagnostic use Luteinizing Hormone / secretion Magnetic Resonance Imaging Pituitary Apoplexy / complications*, diagnosis Pituitary Neoplasms / complications, secretion Recurrence Remission, Spontaneous Thyrotropin / secretion Thyrotropin-Releasing Hormone / diagnostic use |
| Chemical | |
Reg. No./Substance:
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11061-68-0/Insulin; 12629-01-5/Human Growth Hormone; 24305-27-9/Thyrotropin-Releasing Hormone; 33515-09-2/Gonadotropin-Releasing Hormone; 50-02-2/Dexamethasone; 50-23-7/Hydrocortisone; 9002-60-2/Adrenocorticotropic Hormone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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