Document Detail


Rectal tone and brain information processing in irritable bowel syndrome.
MedLine Citation:
PMID:  10877231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied differences in rectal tone between healthy controls, nonpsychiatric irritable bowel syndrome (IBS) patients, and IBS patients with comorbid phobic anxiety disorders to assess the impact of psychiatric comorbidity on rectal tone. The groups were additionally compared with respect to brain information processing of everyday words with emotional content to see if we could identify an association between perception of emotional material in the brain and rectal tone. We found that both nonpsychiatric IBS patients and IBS patients with phobic anxiety disorder had increased baseline rectal tone compared with healthy controls (F = 9.81, P < 0.001). The phobic anxiety patients tended to have increased tone compared with nonpsychiatric IBS patients, but the difference did not reach statistical significance. Similar differences were found in the attentional elements of brain information processing activity assessed by event-related potentials. Rectal tone significantly predicted brain reactivity to emotional words, suggesting that changes in intestinal motor function may influence brain perception.
Authors:
S Blomhoff; S Spetalen; M B Jacobsen; M Vatn; U F Malt
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  45     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-12     Completed Date:  2000-07-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1153-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Psychosomatic and Behavioural Medicine, National Hospital, Oslo, Norway.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anxiety Disorders / complications
Brain / physiology*
Colonic Diseases, Functional / physiopathology*,  psychology*
Emotions
Evoked Potentials
Evoked Potentials, Auditory
Female
Humans
Mental Processes*
Muscle Tonus*
Muscle, Smooth / physiopathology
Rectum / physiopathology*
Reference Values
Regression Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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