Document Detail

Rectal suction biopsy for the diagnosis of Hirschsprung's disease.
MedLine Citation:
PMID:  7212804     Owner:  NLM     Status:  MEDLINE    
The diagnosis of Hirschsprung's disease is at times difficult, particularly in the young patient. Since 1972 we have used rectal suction biopsy as a screening technique in neonates and infants with failure to pass meconium or evidence of obstruction. In addition, it is used to confirm the diagnosis of Hirschsprung's disease when suspected by barium enema study. This technique has been used in 444 patients, 302 of whom were less than one year of age. No anesthesia is necessary, and there have been no associated complications. Only one patient early in the study had an initial misdiagnosis. There have been no false-positive or false-negative specimens since this initial problem, and no patients have undergone inappropriate pull-through procedures for suspected Hirschsprung's disease. It is recommended that all neonates who do not pass meconium in the first 48 hours of life undergo rectal suction biopsy to establish the diagnosis of congenital megacolon.
R J Andrassy; H Isaacs; J J Weitzman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of surgery     Volume:  193     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-05-26     Completed Date:  1981-05-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  419-24     Citation Subset:  AIM; IM    
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MeSH Terms
Biopsy, Needle / instrumentation,  methods*
Child, Preschool
Diagnosis, Differential
Evaluation Studies as Topic
Infant, Newborn
Intestinal Obstruction / pathology
Megacolon / pathology*
Rectum / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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