Document Detail

Rectal mucosal replacement.
MedLine Citation:
PMID:  7362295     Owner:  NLM     Status:  MEDLINE    
Preservation of the rectum in chronic ulcerative colitis or familial polyposis conserves continence at the risk of recurrent disease or malignant change. Replacement of rectal mucosa with a graft of ileum in these benign colonic mucosal diseases conserves fecal continence without the threat of continuing disease or the development of carcinoma. Rectal mucosal replacement with construction of a rectal reservoir includes total colectomy, removal of the rectal mucosa-submucosa and its replacement with an ileal graft. A rectal reservoir is constructed when intestinal continuity is restored. Twenty-nine patients have undergone rectal mucosal replacement; 12 for familial polyposis and 17 for ulcerative colitis. Twenty-five patients have had intestinal continuity restored. Patients have been followed from three months to seven years after the restoration of intestinal continuity. Twenty-three patients have a satisfactory result. Fecal continence has been preserved. Patients pass an average of six stools in a 24 hour period.
D A Peck
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of surgery     Volume:  191     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-05-14     Completed Date:  1980-05-14     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  294-303     Citation Subset:  AIM; IM    
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MeSH Terms
Colitis, Ulcerative / surgery*
Fecal Incontinence / etiology
Ileum / transplantation
Intestinal Mucosa / transplantation*
Intestinal Polyps / genetics,  surgery*
Middle Aged
Postoperative Complications / etiology
Rectal Neoplasms / surgery*
Rectum / surgery*
Transplantation, Autologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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