| Recruitment for phase I of the trials of hypertension prevention. | |
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MedLine Citation:
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PMID: 8398224 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phase I of the Trials of Hypertension Prevention was a multicenter, randomized, controlled trial designed to determine the efficacy of seven nonpharmacologic interventions in reducing blood pressure among persons with high-normal diastolic blood pressure. The initial goal for recruitment was to enroll 2,100 participants over a nine-month period. The two major strategies for reaching potential participants were direct mailings and work site screenings. The yield from the first screening visit to randomization was 13% overall, with clinic-specific yields ranging from 4.5% to 31.7%. After five months of recruitment, approximately 60% of the goal for that point in the recruitment timetable had been randomized. Clinical centers falling short of their goals at that time altered their recruitment strategies and intensified their efforts, and centers that had exceeded their goals recruited additional participants. As a result, 2,182 participants, or 104% of the goal for recruitment, were randomized over a 13-month period. Those clinics using a cohort, or wave, type of enrollment were most successful in achieving their recruitment goals within the prescribed timetable. |
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Authors:
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S Satterfield; N O Borhani; P Whelton; L Goodwin; C Brinkmann; J Charleston; B W Corkery; L Dolan; H Hataway; S Hertert |
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Publication Detail:
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Type: Clinical Trial; Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of preventive medicine Volume: 9 ISSN: 0749-3797 ISO Abbreviation: Am J Prev Med Publication Date: 1993 Jul-Aug |
Date Detail:
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Created Date: 1993-10-26 Completed Date: 1993-10-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8704773 Medline TA: Am J Prev Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 237-43 Citation Subset: IM |
Affiliation:
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Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215-1204. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure Cohort Studies Female Goals Humans Hypertension / prevention & control* Life Style Male Mass Screening Middle Aged Patient Admission / standards* Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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HL37849/HL/NHLBI NIH HHS; HL37852/HL/NHLBI NIH HHS; HL37853/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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