Document Detail

Recruitment for phase I of the trials of hypertension prevention.
MedLine Citation:
PMID:  8398224     Owner:  NLM     Status:  MEDLINE    
Phase I of the Trials of Hypertension Prevention was a multicenter, randomized, controlled trial designed to determine the efficacy of seven nonpharmacologic interventions in reducing blood pressure among persons with high-normal diastolic blood pressure. The initial goal for recruitment was to enroll 2,100 participants over a nine-month period. The two major strategies for reaching potential participants were direct mailings and work site screenings. The yield from the first screening visit to randomization was 13% overall, with clinic-specific yields ranging from 4.5% to 31.7%. After five months of recruitment, approximately 60% of the goal for that point in the recruitment timetable had been randomized. Clinical centers falling short of their goals at that time altered their recruitment strategies and intensified their efforts, and centers that had exceeded their goals recruited additional participants. As a result, 2,182 participants, or 104% of the goal for recruitment, were randomized over a 13-month period. Those clinics using a cohort, or wave, type of enrollment were most successful in achieving their recruitment goals within the prescribed timetable.
S Satterfield; N O Borhani; P Whelton; L Goodwin; C Brinkmann; J Charleston; B W Corkery; L Dolan; H Hataway; S Hertert
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Publication Detail:
Type:  Clinical Trial; Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of preventive medicine     Volume:  9     ISSN:  0749-3797     ISO Abbreviation:  Am J Prev Med     Publication Date:    1993 Jul-Aug
Date Detail:
Created Date:  1993-10-26     Completed Date:  1993-10-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8704773     Medline TA:  Am J Prev Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  237-43     Citation Subset:  IM    
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215-1204.
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MeSH Terms
Blood Pressure
Cohort Studies
Hypertension / prevention & control*
Life Style
Mass Screening
Middle Aged
Patient Admission / standards*
Time Factors
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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