Document Detail


Recruitment and attrition in twin register studies of childhood behavior: the example of the Australian Twin ADHD Project.
MedLine Citation:
PMID:  12537853     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are a growing number of large-scale initiatives for twin registers of children. The Australian Twin ADHD Project (ATAP) is used to illustrate two key limitations which may arise with such studies, namely (1) the importance of including or possibly excluding families in which one or both twins have significant developmental disability, and (2) the selective failure to recruit and/or the selective attrition of families in which parents and children share behavioral difficulties. Initially ATAP excluded 1 in 6 of families whose twins were enrolled in the volunteer-based Australian Twin Registry (ATR), and as more children with significant problems were identified, these families were sequentially excluded. With longitudinal data over ten years, two points about retention were identified: the difficulty of retaining the twins in late adolescence, and the loss of the families whose twins had more ADHD symptoms. We discuss strategies for limiting the loss of families and for ensuring comparability of data across registers with similar interests but different methods of recruitment and exclusion.
Authors:
David A Hay; Michael McStephen; Florence Levy; Jillian Pearsall-Jones
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Twin research : the official journal of the International Society for Twin Studies     Volume:  5     ISSN:  1369-0523     ISO Abbreviation:  Twin Res     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2003-03-04     Completed Date:  2003-03-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9815819     Medline TA:  Twin Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  324-8     Citation Subset:  IM    
Affiliation:
School of Psychology, Curtin University, Perth, WA, Australia. d.hay@curtain.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adolescent Behavior / psychology
Attention Deficit Disorder with Hyperactivity / genetics*,  psychology
Australia
Blood Group Antigens / genetics
Child
Child Behavior
Child, Preschool
Data Collection / methods
Disabled Children / psychology
Diseases in Twins / genetics*
Female
Humans
Longitudinal Studies
Molecular Biology
Patient Dropouts / psychology,  statistics & numerical data*
Patient Selection*
Placentation
Polymorphism, Genetic / genetics
Pregnancy
Questionnaires
Registries / statistics & numerical data*
Twin Studies as Topic / methods*,  statistics & numerical data*
Chemical
Reg. No./Substance:
0/Blood Group Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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