Document Detail

Recreational Exercise Before and During Pregnancy in Relation to Plasma C-Reactive Protein Concentrations in Pregnant Women.
MedLine Citation:
PMID:  25111060     Owner:  NLM     Status:  Publisher    
BACKGROUND: Pregnant women who are physically active have a lower risk of preeclampsia and gestational diabetes than women who were less active. One possible mechanism is a reduction in low-grade inflammation, measured by C-reactive protein (CRP). The association between exercise and CRP in pregnant women, however, has not been adequately investigated.
METHODS: A total of 537 pregnant women enrolled around the 17th week of gestation in the Norwegian Mother and Child Cohort Study from 2003 to 2004 were studied. Self-reported recreational exercise was recalled for both 3 months before pregnancy and early pregnancy. The total energy expenditure from recreational exercise (total recreational exercise, MET-hours/week) was estimated and low-, moderate- and vigorous-intensity exercise was defined. Plasma CRP concentrations were measured during pregnancy.
RESULTS: In adjusted linear regression models, mean CRP concentration was 1.0% lower [95 % confidence interval: -1.9 %, -0.2 %] with each 1 MET-hour/week of total recreational exercise before pregnancy. Additionally, vigorous-intensity exercise before pregnancy was more strongly related to a reduction in CRP levels than low- or moderate-intensity exercise. However, we observed no association of recreational exercise during pregnancy with CRP levels.
CONCLUSIONS: Recreational exercise, especially vigorous before pregnancy, may reduce the risk of maternal inflammation during pregnancy.
Yan Wang; Lea A Cupul-Uicab; Walter J Rogan; Merete Eggesbo; Gregory Travlos; Ralph Wilson; Matthew P Longnecker
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-7
Journal Detail:
Title:  Journal of physical activity & health     Volume:  -     ISSN:  1543-5474     ISO Abbreviation:  J Phys Act Health     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101189457     Medline TA:  J Phys Act Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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