Document Detail

Recovery of tactile function after damage to primary or secondary somatic sensory cortex in infant Macaca mulatta.
MedLine Citation:
PMID:  3346724     Owner:  NLM     Status:  MEDLINE    
These studies were designed to determine the basis for recovery of tactile function after the removal of primary (SI) or secondary (SII) cortex in infant Macaca mulatta. From previous studies we know that although removal of SI or SII in the adult macaque produces severe and irreversible impairment on a variety of tactile tasks, normal function can be obtained after partial or total SI lesions in the infant. From the present studies we have found that, as with SI, neither unilateral nor bilateral removals of SII in infants significantly affected the acquisition of or the performance on size tasks, but did cause a temporary delay in acquisition of texture tasks. Performance on texture threshold tasks was normal. The removal of the remaining SI in a juvenile animal that had received a unilateral SI lesion in infancy did not disrupt the recovered function, indicating that recovery is not mediated by the intact SI. However, when SI and SII were removed together from the same hemisphere in an infant, either sequentially or simultaneously, major impairment in the acquisition of texture tasks followed. These results suggest that although SI and SII are necessary for normal tactile function in the adult macaque, they show an equipotentiality for mediating normal tactile function after damage to either area in infants.
M Carlson; H Burton
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  8     ISSN:  0270-6474     ISO Abbreviation:  J. Neurosci.     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-14     Completed Date:  1988-04-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  833-59     Citation Subset:  IM    
Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110.
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MeSH Terms
Brain Diseases / physiopathology
Discrimination (Psychology) / physiology
Macaca mulatta
Somatosensory Cortex / physiology*,  physiopathology
Thalamus / physiology,  physiopathology
Touch / physiology*
Grant Support

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