| Recovery of heart rate variability in patients with moderate to severe obstructive sleep apnea after 6-month continuous positive airway pressure treatment. | |
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MedLine Citation:
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PMID: 17926981 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the effect of long-term treatment with continuous positive airway pressure (CPAP) on the heart rate variability (HRV) of obstructive sleep apnea (OSA) patients. MATERIAL AND METHOD: Patients with moderate to severe OSA who had never used CPAP treatment were enrolled. Short recording HRV analysis was performed at baseline then at one, three, and six months after CPAP treatment. The measurement included low frequency HRV (LF), high frequency HRV (HF), low frequency to high frequency ratio (LHR), and standard deviation of R-R intervals (SDNN). All domains were measured both during spontaneous and deep breathing. RESULTS: There were 10 patients in the present study, all were men with the mean age of 45 years, mean body mass index 29.3 kg/m2, mean apnea-hypopnea index 60.9 events/hour, and mean average CPAP usage 4.8 hours/night. The HRV showed no significant change after one and three months of CPAP treatment. At 6 months, the only significant change was the SDNN measured after deep breathing (28.80 +/- 9.83 vs. 34.43 +/- 14.23 millisecond, p = 0.032). CONCLUSION: One aspect of heart rate variability in moderate to severe obstructive sleep apnea patients was improved after six month's continuous positive airway pressure treatment. |
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Authors:
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Pimporn Limphanudom; Nitipatana Chierakul; Narongsak Pinyopattarakul; Arth Nana; Chana Naruman; Suwat Tangchityongsiva; Wattana B Wattanapa; Anorut Jenwitheesak |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the Medical Association of Thailand = Chotmaihet thangphaet Volume: 90 ISSN: 0125-2208 ISO Abbreviation: J Med Assoc Thai Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-10-11 Completed Date: 2007-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7507216 Medline TA: J Med Assoc Thai Country: Thailand |
Other Details:
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Languages: eng Pagination: 1530-5 Citation Subset: IM |
Affiliation:
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Division of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autonomic Nervous System
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physiopathology Continuous Positive Airway Pressure* Heart Rate* Humans Male Middle Aged Sleep Apnea, Obstructive / physiopathology*, therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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