Document Detail

Recovery of function after sciatic nerve crush lesion in rats selected for diverging locomotor activity in the open field.
MedLine Citation:
PMID:  9464637     Owner:  NLM     Status:  MEDLINE    
The relation between recovery of function following a sciatic nerve crush lesion and an individual behavioural characteristic, the locomotor activity in an open field, was investigated in rats. Ten high-active (HA) and ten low-active (LA) rats were selected from a stock of sixty male, random-bred Wistar rats, by measuring travelled distance in an open field. Subsequently, both HA and LA rats underwent an unilateral sciatic nerve crush. Recovery of motor function revealed no significant differences between both groups, whereas recovery of sensory function in HA rats was significantly more rapid than in the LA rats (P < 0.01). These observations suggest the existence of a relationship between individual behavioural characteristics, and the sensory recovery of nerve function following crush lesion in rats.
N L van Meeteren; J H Brakkee; P J Helders; G Croiset; W H Gispen; V M Wiegant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroscience letters     Volume:  238     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-04-24     Completed Date:  1998-04-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  131-4     Citation Subset:  IM    
Rudolf Magnus Institute for Neurosciences, Utrecht University, Faculty of Medicine, Department of Medical Pharmacology, The Netherlands.
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MeSH Terms
Adrenal Glands / pathology
Electric Stimulation
Exploratory Behavior / physiology*
Motor Activity / physiology*
Movement Disorders / etiology,  physiopathology
Nerve Crush
Nerve Regeneration*
Organ Size
Rats, Wistar
Sciatic Nerve / injuries,  physiology*
Sensation Disorders / etiology,  physiopathology
Thymus Gland / pathology
Time Factors

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