Document Detail


Recovery from giant cell myocarditis with ECMO support and utilisation of polyclonal antithymocyte globulin: a case report.
MedLine Citation:
PMID:  16755453     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Giant cell myocarditis (GCM) is a rare and frequently fatal disorder. Patients suffer of ventricular arrhythmias or congestive heart failure. Here we describe a patient with cardiogenic shock and histological verified GCM. The patient was saved by implantation of extracorporeal membrane oxygeneation (ECMO) device and concomitant application of Rabbit antithymocyte globuline (rATG, Thymoglobulin, Sangstat), cyclosporine, and steroids in the acute event. 12 months after the crisis the patient evidences NYHA class I heart function and only a moderate impairment of heart function (EF 55%). The novel utilisation of ECMO in GCM related cardiogenic shock and application of rATG have prooven life-saving in this patient. Studies utilizing rATG in the treatment of GCM are warrented.
Authors:
H J Ankersmit; R Ullrich; B Moser; K Hoetzenecker; S Hacker; P German; C Krenn; R Horvat; M Grimm; E Wolner; A Zuckermann
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  54     ISSN:  0171-6425     ISO Abbreviation:  Thorac Cardiovasc Surg     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-06     Completed Date:  2006-11-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  278-80     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Surgery, Medical University of Vienna, General Hospital of Vienna, Vienna, Austria. hjankersmit@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Antilymphocyte Serum / therapeutic use*
Extracorporeal Membrane Oxygenation*
Giant Cells / pathology*
Humans
Immunologic Factors / therapeutic use*
Male
Middle Aged
Myocarditis / drug therapy,  pathology,  therapy*
Shock, Cardiogenic / drug therapy,  pathology,  therapy*
T-Lymphocytes / immunology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antilymphocyte Serum; 0/Immunologic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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