Document Detail


Recovery from complete atrioventricular block caused by idiopathic giant cell myocarditis after corticosteroid therapy.
MedLine Citation:
PMID:  9583449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Giant cell myocarditis (GCM) is a rapidly progressive disease that leads to ventricular tachycardia or high-grade atrioventricular (A-V) block, frequently requiring a pacemaker. A 64-year-old woman developed syncope as a result of idiopathic GCM with A-V block. She required both a temporary and a permanent pacemaker. Two-dimensional echocardiography showed severely reduced wall motion. There was no histologic or clinical evidence to suggest sarcoidosis. Despite treatment with diuretics and an angiotensin-converting enzyme inhibitor, exertional dyspnea persisted. She received prednisolone 4 months after the onset of complete A-V block in the late phase of GCM. Prednisolone improved A-V nodal conduction in spite of the fact that there was no influence from LV wall motion, and sinus rhythm has continued for more than 2 years. In this patient, prednisolone was effective in the treatment of GCM.
Authors:
H Hanawa; T Izumi; Y Saito; Y Ochiai; Y Okura; T Inomata; S Hirono; Y Ogawa; R Saito; M Kodama; N Higuma; Y Aizawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  62     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-07-14     Completed Date:  1998-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  211-4     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Niigata University School of Medicine, Asahimachi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents / therapeutic use*
Echocardiography
Female
Giant Cells
Heart Block / drug therapy*,  etiology*,  physiopathology
Humans
Middle Aged
Myocarditis / complications*,  pathology,  physiopathology
Prednisolone / therapeutic use*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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