| Recovery from adaptation of the action potential in idiopathic sudden sensorineural hearing loss investigated using a paired-click stimulation paradigm. | |
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MedLine Citation:
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PMID: 21970787 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Abstract Conclusion: We studied the compound action potential (AP) recovery from adaptation (AP recovery) in idiopathic sensorineural hearing loss (iSSNHL). Abnormal AP recovery was demonstrated in 15 of 45 patients, consisting of increased recovery (iR) over the normal range in 11 ears and decreased recovery (dR) under the normal range in 4 ears. The mechanisms for occurrence and clinical significance of these phenomena are currently unknown. Objectives: The purpose of this study was to investigate the pathologic features of AP recovery in iSSNHL. Methods: Forty-five subjects with iSSNHL were enrolled and 18 normal-hearing subjects participated to assess the normal range of AP recovery. Equilevel paired clicks with inter-click interval from 5 to 100 ms were applied as acoustic stimuli. Results: Eleven ears with iR and four ears with dR were found. The audiogram patterns of 11 iR and 4 dR ears exhibited 10 flat types, 3 high frequency loss types, and 2 low frequency loss types. Only 2 of 11 subjects with iR ears and 0 of 4 with dR ears complained of vertigo. No significant difference was observed in the comparison between AP threshold and hearing level of iR with those of normal recovery (nR) within the normal range. |
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Authors:
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Toru Ohashi; Hirohito Nishino; Yoko Arai; Takashi Otsuka; Izumi Koizuka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 131 ISSN: 1651-2251 ISO Abbreviation: Acta Otolaryngol. Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-10-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: England |
Other Details:
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Languages: eng Pagination: 1165-71 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Hadano Red Cross Hospital. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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