Document Detail


Recovery characteristics using single-breath 8% sevoflurane or propofol for induction of anaesthesia in day-case arthroscopy patients.
MedLine Citation:
PMID:  10023274     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the induction and recovery characteristics following inhalational induction with 8% sevoflurane in nitrous oxide and oxygen compared with intravenous propofol in 40 patients presenting for arthroscopy of the knee. Patients were randomly allocated to receive either induction agent, and anaesthesia was then maintained with sevoflurane in oxygen and nitrous oxide. A computerised test of hand--eye co-ordination and a p-deletion test were used to measure psychomotor recovery. The sevoflurane group had a faster onset of anaesthesia time. No significant differences between the groups were found in time to eye opening or psychomotor tests. Nausea and vomiting scores were significantly higher at 30 min in the sevoflurane group (p = 0.04); this difference was no longer significant by 90 min. We conclude that inhalational induction with sevoflurane in these patients has no important clinical advantages and causes more nausea and vomiting than propofol.
Authors:
A K Dashfield; D J Birt; J Thurlow; I G Kestin; J A Langton
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia     Volume:  53     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-02-25     Completed Date:  1999-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1062-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Anaesthesia, Derriford Hospital, Plymouth, UK.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Ambulatory Surgical Procedures*
Anesthesia Recovery Period
Anesthetics, Inhalation* / adverse effects
Anesthetics, Intravenous
Arthroscopy
Endoscopy*
Female
Humans
Knee Joint / surgery*
Male
Methyl Ethers* / adverse effects
Middle Aged
Postoperative Nausea and Vomiting / chemically induced
Postoperative Period
Propofol
Psychomotor Performance / drug effects
Chemical
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 0/Methyl Ethers; 2078-54-8/Propofol; 28523-86-6/sevoflurane
Comments/Corrections
Comment In:
Anaesthesia. 2000 Jun;55(6):594-5   [PMID:  10866732 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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