Document Detail

Recovery of anticipatory activity to restricted feeding in rats with ventromedial hypothalamic lesions.
MedLine Citation:
PMID:  6505064     Owner:  NLM     Status:  MEDLINE    
Entrainment of circadian activity rhythms to a fixed daily mealtime was measured in intact and ventromedial hypothalamic (VMH) lesioned rats housed in tilt-cages. Intact rats showed a clear increase in activity for 2-3 hr prior to the 2 hr daytime feeding period. Anticipatory activity in lesioned rats was attenuated or absent during restricted feeding 5-9 weeks after surgery, but was evident in all rats, even those bearing apparently total VMH damage, during a second restricted feeding schedule 14-21 weeks after surgery. These results show recovery of function and argue against a necessary role for the VMH in food entrained rhythms.
R E Mistlberger; A Rechtschaffen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Physiology & behavior     Volume:  33     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1985-01-09     Completed Date:  1985-01-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  227-35     Citation Subset:  IM    
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MeSH Terms
Arousal / physiology*
Body Weight
Brain Mapping
Circadian Rhythm*
Conditioning, Operant / physiology
Feeding Behavior / physiology*
Food Deprivation
Motor Activity / physiology*
Rats, Inbred Strains
Reinforcement Schedule
Ventromedial Hypothalamic Nucleus / physiology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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