| Recordings from the facial motonucleus in rats with signs of hemifacial spasm. | |
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MedLine Citation:
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PMID: 7870279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We recorded evoked potentials from the facial motonucleus of rats in response to electrical stimulation of the temporal branch of the facial nerve in which chronic irritation from a blood vessel had caused the development of an abnormal muscle response. The abnormal muscle response that can be recorded from face muscles that are innervated by one branch of the facial nerve in response to electrical stimulation of a different branch is regarded to be a sign of hemifacial spasm. In the recordings from the motonucleus in rats that showed such an abnormal muscle response (model rats) there was a late component at a latency of about 5 msec, in addition to the early component with a latency of 1.5-2.5 msec that is also observed in normal rats. The latency of the electromyographic potentials recorded from the mentalis-orbicularis oris muscles in response to stimulation of the facial motonucleus was about 2 msec. The latency of the abnormal muscle response obtained from the mentalis muscle in the model rats was about 7 msec. This value is close to the sum of the conduction time from the motonucleus to the mentalis muscle (2 msec) and the latency of the late response from the motonucleus (5 msec). Similar results were obtained in rats in which the facial nerve had been chronically stimulated electrically and which had developed an abnormal muscle response. The results of this study further support the hypothesis that the hyperactivity of the facial motonucleus is the pathophysiology of hemifacial spasm. |
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Authors:
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A Kuroki; A R Møller; S Saito |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Neurological research Volume: 16 ISSN: 0161-6412 ISO Abbreviation: Neurol. Res. Publication Date: 1994 Oct |
Date Detail:
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Created Date: 1995-03-27 Completed Date: 1995-03-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7905298 Medline TA: Neurol Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 389-92 Citation Subset: IM |
Affiliation:
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Department of Neurological Surgery, University of Pittsburgh School of Medicine, PA 15213. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Electric Stimulation Evoked Potentials Facial Muscles / innervation, physiology, physiopathology* Facial Nerve / blood supply, physiology, physiopathology* Female Motor Neurons / physiology Myelin Sheath / physiology Rats Rats, Wistar Reference Values Spasm / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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