| Recording respiratory parameters in patients with epilepsy. | |
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MedLine Citation:
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PMID: 19909325 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Anecdotal evidence and data from small studies suggest that respiratory changes occur in both complex partial and generalized seizures. Our understanding of sudden unexpected death in epilepsy (SUDEP) may be furthered by recording and analyzing these changes. Investigators at the Jules Thorn Telemetry Unit at the National Hospital for Neurology and Neurosurgery have documented a range of respiratory parameters (respiratory effort, airflow, oxygen saturation) in conjunction with time-locked audio-video electroencephalograms and electrocardiograms to provide a more complete picture of the physiologic changes that occur during seizures. Cardiorespiratory information on 79 seizures (70 complex partial, nine generalized) in 37 patients (20 male, 17 female) is presented. Whereas tachycardia was a common ictal feature, bradycardia was seen only rarely and tended to follow a period of apnea. Apnea occurred in 100% of generalized seizures and 39% of complex partial seizures. Apnea was predominantly central and lasted for 10-75 s (mean duration 29 s). Central apnea may be one of the major, although by no means exclusive, ictal events predisposing to SUDEP. |
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Authors:
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F Walker; D R Fish |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Epilepsia Volume: 38 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 1997 Nov |
Date Detail:
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Created Date: 2009-11-13 Completed Date: 2010-08-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: S41-2 Citation Subset: IM |
Affiliation:
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Jules Thorn Telemetry Unit, The National Hospital for Neurology and Neurosurgery, Queen Square, London, England. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Bradycardia / diagnosis, epidemiology Comorbidity Death, Sudden / epidemiology Electrocardiography / methods, statistics & numerical data Electroencephalography / methods, statistics & numerical data Epilepsy / diagnosis*, epidemiology, mortality Epilepsy, Complex Partial / diagnosis, epidemiology Female Heart Rate / physiology Humans Male Middle Aged Oximetry Pulmonary Ventilation Respiratory Function Tests / methods*, statistics & numerical data Sleep Apnea, Central / diagnosis*, epidemiology Tachycardia / diagnosis, epidemiology Telemetry / methods, statistics & numerical data |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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