Document Detail


Reconstruction of cell lineage and spatiotemporal pattern formation of the mesoderm in the amphipod crustacean Orchestia cavimana.
MedLine Citation:
PMID:  22374787     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Cell lineage studies in amphipods have revealed an early restriction of blastomere fate. The mesendodermal cell lineage is specified with the third cleavage of the egg. We took advantage of this stereotyped mode of development by fluorescently labeling the mesodermal precursors in embryos of Orchestia cavimana and followed the morphogenesis of the mesodermal cell layer through embryonic development. Results: The mesoderm of the trunk segments is formed by a very regular and stereotypic cell division pattern of the mesoteloblasts and their segmental daughters. The head mesoderm in contrast is generated by cell movements and divisions out of a mesendodermal cell mass. Our reconstructions reveal the presence of three different domains within the trunk mesoderm of the later embryo. We distinguish a cell group median to the limbs, a major central population from which the limb mesoderm arises and a dorsolateral branch of mesodermal cells. Conclusions: Our detailed description of mesodermal development relates different precursor cell groups to distinct muscle groups of the embryo. A dorsoventral subdivision of mesoderm is prepatterned within the longitudinal mesodermal columns of the germ-band stage. This makes amphipods excellent crustacean models for studying mesodermal differentiation on a cellular and molecular level. Developmental Dynamics, 2012. © 2012 Wiley Periodicals, Inc.
Authors:
Vera S Hunnekuhl; Carsten Wolff
Related Documents :
11167077 - Real-time molecular and cellular analysis: the new frontier of drug discovery.
19230647 - Entrapment of live microbial cells in electropolymerized polyaniline and their use as u...
19416527 - Scale-free flow of life: on the biology, economics, and physics of the cell.
20803587 - A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on bo...
19956857 - Cell cycle effects of fatty acid derivatives of cytarabine, cp-4055, and of gemcitabine...
6157837 - Antigenic and immunogenic characteristics of nuclear and membrane-associated simian vir...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-10
Journal Detail:
Title:  Developmental dynamics : an official publication of the American Association of Anatomists     Volume:  -     ISSN:  1097-0177     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9201927     Medline TA:  Dev Dyn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
Laboratory for Evolution and Development, Department of Zoology, Cambridge, United Kingdom.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Frequent activating GNAS mutations in villous adenoma of the colorectum.
Next Document:  Differential effects of substrate modulus on human vascular endothelial, smooth muscle, and fibrobla...