| Reconstruction and exploration of virtual middle-ear models derived from micro-CT datasets. | |
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MedLine Citation:
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PMID: 20100558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Middle-ear anatomy is integrally linked to both its normal function and its response to disease processes. Micro-CT imaging provides an opportunity to capture high-resolution anatomical data in a relatively quick and non-destructive manner. However, to optimally extract functionally relevant details, an intuitive means of reconstructing and interacting with these data is needed. MATERIALS AND METHODS: A micro-CT scanner was used to obtain high-resolution scans of freshly explanted human temporal bones. An advanced volume renderer was adapted to enable real-time reconstruction, display, and manipulation of these volumetric datasets. A custom-designed user interface provided for semi-automated threshold segmentation. A 6-degrees-of-freedom navigation device was designed and fabricated to enable exploration of the 3D space in a manner intuitive to those comfortable with the use of a surgical microscope. Standard haptic devices were also incorporated to assist in navigation and exploration. RESULTS: Our visualization workstation could be adapted to allow for the effective exploration of middle-ear micro-CT datasets. Functionally significant anatomical details could be recognized and objective data could be extracted. CONCLUSIONS: We have developed an intuitive, rapid, and effective means of exploring otological micro-CT datasets. This system may provide a foundation for additional work based on middle-ear anatomical data. |
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Authors:
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Dong H Lee; Sonny Chan; Curt Salisbury; Namkeun Kim; Kenneth Salisbury; Sunil Puria; Nikolas H Blevins |
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Publication Detail:
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Type: In Vitro; Journal Article Date: 2010-01-25 |
Journal Detail:
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Title: Hearing research Volume: 263 ISSN: 1878-5891 ISO Abbreviation: Hear. Res. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-08-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7900445 Medline TA: Hear Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 198-203 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Otolaryngology-HNS, Stanford University, Stanford, CA 94305, USA. dhoonlee.biz+elsevier@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cadaver Databases, Factual Ear, Middle / anatomy & histology*, physiology, radiography* Humans Image Processing, Computer-Assisted Models, Anatomic* Software Temporal Bone / anatomy & histology, radiography User-Computer Interface X-Ray Microtomography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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