Document Detail


Recommendations for the use of cardiac troponin measurement in acute cardiac care.
MedLine Citation:
PMID:  20685679     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The release of cardiomyocyte components, i.e. biomarkers, into the bloodstream in higher than usual quantities indicates an ongoing pathological process. Thus, detection of elevated concentrations of cardiac biomarkers in blood is a sign of cardiac injury which could be due to supply-demand imbalance, toxic effects, or haemodynamic stress. It is up to the clinician to determine the most probable aetiology, the proper therapeutic measures, and the subsequent risk implied by the process. For this reason, the measurement of biomarkers always must be applied in relation to the clinical context and never in isolation. There are a large number of cardiac biomarkers, but they can be subdivided into four broad categories, those related to necrosis, inflammation, haemodynamic stress, and/or thrombosis. Their usefulness is dependent on the accuracy and reproducibility of the measurements, the discriminatory limits separating pathology from physiology, and their sensitivity and specificity for specific organ damage and/or disease processes. In recent years, cardiac biomarkers have become important adjuncts to the delivery of acute cardiac care. Therefore, the Working Group on Acute Cardiac Care of the European Society of Cardiology established a committee to deal with ongoing and newly developing issues related to cardiac biomarkers. The intention of the group is to outline the principles for the application of various biomarkers by clinicians in the setting of acute cardiac care in a series of expert consensus documents. The first of these will focus on cardiac troponin, a pivotal marker of cardiac injury/necrosis.
Authors:
Kristian Thygesen; Johannes Mair; Hugo Katus; Mario Plebani; Per Venge; Paul Collinson; Bertil Lindahl; Evangelos Giannitsis; Yonathan Hasin; Marcello Galvani; Marco Tubaro; Joseph S Alpert; Luigi M Biasucci; Wolfgang Koenig; Christian Mueller; Kurt Huber; Christian Hamm; Allan S Jaffe;
Related Documents :
22739559 - Renal infarction as a presentation of austrian syndrome: thromboembolic phenomenon of p...
21982989 - Paroxysmal supraventricular tachycardia in an octogenarian.
22498449 - A rare combination of left ventricular noncompaction, patent ductus arteriosus, and per...
21644989 - Occlusion of left and right coronary arteries and coronary sinus following blunt chest ...
22679259 - Impending myocardial rupture: is an early surgical treatment enough?
21822449 - Recurrent small bowel infarction in a young man: polycythaemia or vasculitis?
22348409 - Transthoracic real time three-dimensional echocardiography in impella placement.
22481459 - Cardiac metastasis of hepatocellular carcinoma in a young non-cirrhotic patient, to the...
15732029 - Managed care patients with heart failure: spectrum of ventricular dysfunction and predi...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-03
Journal Detail:
Title:  European heart journal     Volume:  31     ISSN:  1522-9645     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  2197-204     Citation Subset:  IM    
Affiliation:
Department of Medicine and Cardiology, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus C, Denmark. kristhyg@rm.dk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Unique haemodynamics in the patient with residual native aortic regurgitation who underwent apicoaor...
Next Document:  Computed tomography angiography: uncommon findings in an adult patient with unrepaired Tetralogy of ...